mouse CD47 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-255016
Availability:
Immediate
Name:
AAV-m-CD47
This is an AAV expressing Mouse Cd47.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Cd47
- Gene Name
- CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
- Gene ID
- 16423
- Gene Synonyms
- 9130415E20Rik; AA407862; AI848868; AW108519; B430305P08Rik; IAP; Itgp
- ORF Size
- 975 bp
- RefSeq#
- BC012667
- Gene Description
- Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
- UniGene ID
- Mm.390865
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