human FMO2 Over-expression AAV

Name 
AAV-h-FMO2
Cat No 
AAV-209181
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human FMO2.

AAV-209181
AAV-h-FMO2

Ready-to-use AAV expressing Human FMO2 (flavin containing monooxygenase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FMO1B1
Description (Vector)
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Gene ID
2327
Gene Name (Vector)
flavin containing monooxygenase 2
Gene Symbol
FMO2
HGNC ID
HGNC:3770
ORF Size (aa)
1416
ORF Size (bp)
1416 bp
RefSeq ID
NM_001460
RefSeq Synonyms
NM_001460, NM_001301347, BC005894,
Species
human
UniGene ID
Hs.144912

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.