human FBXW8 Over-expression AAV
This is an AAV expressing Human FBXW8.
AAV-208842
AAV-h-FBXW8
Ready-to-use AAV expressing Human FBXW8 (F-box and WD repeat domain containing 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FBW6; FBW8; FBX29; FBXO29; FBXW6
Description (Vector)
FBXW8 encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
26259
Gene Name (Vector)
F-box and WD repeat domain containing 8
Gene Symbol
FBXW8
HGNC ID
HGNC:13597
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
RefSeq ID
NM_012174
RefSeq Synonyms
NM_153348, NM_012174, BC037296,
Species
human
UniGene ID
Hs.696428
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.