human EXOG Over-expression AAV

Name
AAV-h-EXOG

Cat No
AAV-208183

Availability
4-5 weeks

This is an AAV expressing Human EXOG.

AAV-208183

AAV-h-EXOG

Ready-to-use AAV expressing Human EXOG (exo/endonuclease G). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ENDOGL1; ENDOGL2; ENGL; ENGL-a; ENGL-b; ENGLA; ENGLB

Description (Vector)

EXOG encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.

Gene ID

9941

Gene Name (Vector)

exo/endonuclease G

Gene Symbol

EXOG

HGNC ID

HGNC:3347

ORF Size (aa)

687

ORF Size (bp)

687 bp

RefSeq ID

NM_005107

RefSeq Synonyms

NM_005107, NM_001318959, NM_001318958, NM_001318957, NM_001318956, NM_001318955, NM_001318954, NM_001145464, BC104213, BC104212,

Species

human

UniGene ID

Hs.517897

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.