human EXOC1 Over-expression AAV

Name 
AAV-h-EXOC1
Cat No 
AAV-208173
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EXOC1.

AAV-208173
AAV-h-EXOC1

Ready-to-use AAV expressing Human EXOC1 (exocyst complex component 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BM-102; exocyst complex component 1; exocyst complex component Sec3; SEC3; SEC3L1; SEC3-like 1; SEC3P
Description (eCommerce)
Sec3 is a component of the exocyst complex, a multisubunit complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Description (Vector)
EXOC1 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
55763
Gene Name (eCommerce)
exocyst complex component 1
Gene Name (Vector)
exocyst complex component 1
Gene Symbol
EXOC1
HGNC ID
HGNC:30380
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2685
ORF Size (bp)
2685 bp
Protein Name (eCommerce)
Exocyst complex component 1
RefSeq ID
NM_018261
RefSeq Synonyms
NM_178237, NM_018261, NM_001024924, BC094751,
Research Areas
Insulin Signaling,Signal Transduction,Transport
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
Sec3 is a component of the exocyst complex, a multisubunit complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
UniGene ID
Hs.269665
UniProt ID (eCommerce)
Q9NV70

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.