human ERN1 Over-expression AAV

Name
AAV-h-ERN1

Cat No
AAV-208088

Availability
4-5 weeks

This is an AAV expressing Human ERN1.

AAV-208088

AAV-h-ERN1

Ready-to-use AAV expressing Human ERN1 (endoplasmic reticulum to nucleus signaling 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hIRE1p; IRE1; IRE1a; IRE1P

Description (Vector)

ERN1 is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Gene ID

2081

Gene Name (Vector)

endoplasmic reticulum to nucleus signaling 1

Gene Symbol

ERN1

HGNC ID

HGNC:3449

ORF Size (aa)

2934

ORF Size (bp)

2934 bp

RefSeq ID

NM_001433

RefSeq Synonyms

NM_001433, BC130407, BC130405,

Species

human

UniGene ID

Hs.700027

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.