human EPX Over-expression AAV

Name 
AAV-h-EPX
Cat No 
AAV-208033
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EPX.

AAV-208033
AAV-h-EPX

Ready-to-use AAV expressing Human EPX (eosinophil peroxidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EPO; EPP; EPX-PEN; EPXD
Description (Vector)
EPX is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.
Gene ID
8288
Gene Name (Vector)
eosinophil peroxidase
Gene Symbol
EPX
HGNC ID
HGNC:3423
ORF Size (aa)
2148
ORF Size (bp)
2148 bp
RefSeq ID
NM_000502
RefSeq Synonyms
NM_000502, BC111602,
Species
human
UniGene ID
Hs.279259

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.