human EPN2 Over-expression AAV

Name 
AAV-h-EPN2
Cat No 
AAV-208012
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human EPN2.

AAV-208012
AAV-h-EPN2

Ready-to-use AAV expressing Human EPN2 (epsin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EHB21; Eps15 binding protein; EPS-15-interacting protein 2; epsin-2
Description (eCommerce)
EPS-15-interacting protein 2 (EPN2) interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. EPN2 is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 22905)].
Description (Vector)
EPN2 encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene ID
22905
Gene Name (eCommerce)
epsin 2
Gene Name (Vector)
epsin 2
Gene Symbol
EPN2
HGNC ID
HGNC:18639
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
Protein Name (eCommerce)
Epsin-2
RefSeq ID
NM_148921
RefSeq Synonyms
NM_148921, NM_014964, NM_001102664, BC093974, BC093972,
Research Areas
EGFR Signaling,Notch Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,developmental_biology
Species
human
Target Sentence
EPS-15-interacting protein 2 (EPN2) interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. EPN2 is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 22905)].
UniGene ID
Hs.715517
UniProt ID (eCommerce)
O95208

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.