human EDNRB Over-expression AAV
This is an AAV expressing Human EDNRB.
AAV-207570
AAV-h-EDNRB
Ready-to-use AAV expressing Human EDNRB (endothelin receptor type B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABCDS; ET-B; ET-BR; ETB; ETB1; ETBR; ETRB; HSCR; HSCR2; WS4A
Description (Vector)
EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
1910
Gene Name (Vector)
endothelin receptor type B
Gene Symbol
EDNRB
HGNC ID
HGNC:3180
ORF Size (aa)
1329
ORF Size (bp)
1329 bp
RefSeq ID
NM_000115
RefSeq Synonyms
NM_003991, NM_001201397, NM_001122659, NM_000115, BC014472,
Species
human
UniGene ID
Hs.82002
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.