NFKb-Luciferase adenovirus

Product Category: Pre-packaged Ready-to-use Adenovirus

Catalog No. 1740

Viral Backbone: human Adenovirus Type5 (dE1/E3)

Description:

Expression of the Photinus pyralis (firefly) luciferase gene is controlled by a synthetic promoter that contains direct repeats of the transcription recognition sequences for the binding sites for nuclear factor κB (NFkB).

When this Luciferase reporter adenovirus and an uncharacterized gene are cotransfected into mammalian cells, the activation of endogenous protein kinases initiated by the cotransfected gene product will result in the activation of corresponding trans-activators which in turn stimulate luciferasae expression.

Titer: 1x10¹⁰ PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

Published reference for this product:

• Epigenetic imprinting by commensal probiotics inhibits the IL-23/IL-17 axis in an in vitro model of the intestinal mucosal immune system.
  Journal of Leukocyte Biology (2012)

• Inhibition of NF‐κB activity by HIV‐1 Vpr is dependent on Vpr binding protein.
  Journal of Cellular Physiology (2012)

Catalog No.	Tag	Promoter		Species	Price **
1740				Firefly	$475.00

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