Diablo homolog (Drosophila) adenovirus
Product Name: Ad-DIABLO
Product Category: Pre-packaged Ready-to-use Adenovirus
Catalog No. 1587
Viral Backbone: human Adenovirus Type5 (dE1/E3)
Gene Name: DIABLO
Gene Alias: SMAC, SMAC3, DIABLO, DIABLO-S
GeneBank Number: BC011909
Smac (for second mitochondria-derived activator of caspase, also designated DIABLO in mouse for direct IAP [inhibitor of apoptosis protein] binding protein with low PI) promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding IAPs and removing their inhibitory activity. In healthy cells, Smac resides in the mitochondria, but when cells undergo apoptosis, Smac is released into the cytosol.
Titer: 1x1010 PFU/ml
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.