Mitogen-activated protein kinase 3 adenovirus
Product Name: Ad-ERK1
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Gene Name: ERK1
Gene Alias: ERK1, MAPK3, PRKM3, P44ERK1, P44MAPK, ERK-1
GeneBank Number: BC013992
Description: The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, which are encoded by ERK 1 and ERK 2, respectively. Both proteins are regulated by dual phosphorylation on specific tyrosine and threonine residues mapping within a characteristic Thr-Glu-Tyr motif. In response to activation, both MAP kinases phosphorylate downstream components on serine and threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. ERK 3 is a MAP kinase-related protein. The human homolog of ERK 3 has also been cloned and shown to encode a 97 kDa protein. ERK 5 has been identified as an 815 amino acid protein that functions as a substrate for MEK-5, but not for MEK-1 or MEK-2. ERK 6 (also designated SAPK3) is highly expressed in human skeletal muscle and appears to function as a signal transducer during differentiation of myoblasts to myotubes.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
References: - The Receptor Tyrosine Kinase Epha2 Promotes Mammary Adenocarcinoma Tumorigenesis And Metastatic Progression In Mice By Amplifying Erbb2 Signaling
J Clin Invest.. 2008. 118(1):64-78
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1585 |
|
CMV |
|
human |
$690.00 |
|
