SMT3 suppressor of mif two 3 homolog 3 (yeast) adenovirus
Product Name: Ad-SUMO3
Product Category: Pre-packaged Ready-to-use Adenovirus
Catalog No. 1571
Viral Backbone: human Adenovirus Type5 (dE1/E3)
Gene Name: SUMO3
Gene Alias: SMT3A, SUMO3, SMT3H1, SUMO-3
GeneBank Number: BC008420
Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S proteosome. Additional members of the Ub-like protein family include the small ubiquitin-related modifier (SUMO) proteins SUMO-1, 2 and 3. Sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. NEDD4 is a Ub protein ligase that interacts with the epithelial Na+ channel (ENaC) to regulate cellular Na+ concentration. Two isoforms, designated NEDD4-1 and NEDD4-2 exist. NEDD8 functions as an important regulatory component of cell proliferation.
Titer: 1x1010 PFU/ml
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.