Phosphatase and tensin homolog

Product Category: human Adenovirus Type5 (dE1/E3)

Gene Name: PTEN

Gene Alias: BZS, MHAM, TEP1, MMAC1, PTEN1

GeneBank Number: BC005821

Description:

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

Titer: 1x10¹⁰ PFU/ml *

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Cat. No.	Tag	Promoter		Species	Price **
1547		CMV		human	$445.00

• * titer may vary depends on batch
  
• ** Price for US/Canada customers only, please inquire about international pricing.