S-phase kinase-associated protein 2 (p45) adenovirus

Product Category: Ready-use human Adenovirus Type5 (dE1/E3)

Gene Name: SKP2

Gene Alias: FBL1, FLB1, SKP2, FBXL1

GeneBank Number: BC007441

Description:

Cyclin A-Cdk2 kinase activity is essential for progression of the cell through S phase. Skp1 p19 and Skp2 p45 are elements of the cyclin A-Cdk2 S phase kinase. The binding of p19 to cyclin A-Cdk2 is p45-dependent, and levels of p45 are substantially increased in transformed cells. Thus, the modulation of Skp2 p45 expression may result in changes in cell cycle control that contribute to the process of cell transformation.

Titer: 1x10¹⁰ PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

References:

• Transcriptional regulation of the S-Phase kinase-associated protein 2 by the NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cells
  JBC. 2011. :10.1074/jbc.M111.295840

Catalog No.	Tag	Promoter		Species	Price **
1546		CMV		human	$475.00

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