Retinoic acid receptor, alpha adenovirus
Product Name: Ad-RARa
Product Category: Pre-packaged Ready-to-use Adenovirus
Catalog No. 1544
Viral Backbone: human Adenovirus Type5 (dE1/E3)
Gene Name: RAR-A
Gene Alias: RAR, RARA, NR1B1
GeneBank Number: BC008727
Retinoids are metabolites of vitamin A (retinol) that represent an important group of signaling molecules during vertebrate development and tissue differentiation. Retinoic acid receptors (RARs) include RAR-alpha, RAR-beta and RAR-gamma, each of which has a high affinity for all transretinoic acids. Members of the retinoid X receptor (RXR) family, RXR-alpha, RXR-beta1, RXR-beta2 and RXR-gamma, are activated by 9-cis-retinoic acid, a stereo- and photoisomer of all transretinoic acids that is expressed in vivo in both liver and kidney and may represent a widely used hormone. The RAR-related orphan nuclear receptors (ROR) bind DNA as monomers and include ROR-alpha, ROR-beta and ROR-gamma. DAX-1 binds to retinoic acid response elements to mediate transcription. FXR (activated by farnesol and related metabolites) binds RXR to form a heterodimer, which subsequently binds IR-1 elements.
Titer: 1x1010 PFU/ml
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.