Down syndrome critical region gene 1 adenovirus
|Name:|| Ad-DSCR1 |
|Cat. No. || 1539|
|Category:|| Pre-packaged Ready-to-use Adenovirus|
|Gene Name:||human DSCR1|
|Gene Alias:|| CSP1, DSC1, RCN1, DSCR1, MCIP1, ADAPT78|
|NCBI RefSeq:|| BC002864|
|Viral Backbone:|| human Adenovirus Type5 (dE1/E3)|
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Titer: 1x1010 PFU/ml
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.