TNF receptor-associated factor 4 adenovirus
Product Name: Ad-TRAF4
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Gene Name: TRAF4
Gene Alias: CART1, MLN62, RNF83, TRAF4
GeneBank Number: BC001769
Description: TNF receptor-associated factors 1 and 2 (TRAF1 and TRAF2) are two related proteins that form a heterodimeric complex that associates with the cytoplasmic domain of the tumor necrosis factor (TNF) receptor type 2. A third member of this family, TRAF3 (also designated CD40bp or CRAF1), associates with the cytoplasmic domain of CD40. Three additional members of the TRAF/CRAF family of signaling intermediates include TRAF4 (also designated CART1), TRAF5 and TRAF6. TRAF4 has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1511 |
|
CMV |
|
human |
$690.00 |
|
