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Ataxia telangiectasia mutated adenovirus


Product Name: Ad-ATM

Product Category: Ready-use human Adenovirus Type5 (dE1/E3)

Gene Name: ATM

Gene Alias: AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, ATM

GeneBank Number: BC022307

Description:

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Titer: 1x1010 PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

Catalog No. Tag Promoter Species Price **
1491 CMV human $475.00

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