Ataxia telangiectasia mutated Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: 1491
Availability:
Immediate
Name:
Ad-ATM
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
$475.00
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV (ubiquitous)
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- Volume
- 200ul
- Titer
- 1x10^10 PFU/ml
Gene Details
- Species
- Human
- Gene Symbol
- ATM
- Gene ID
- 472
- Gene Synonyms
- AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, ATM
- RefSeq#
- BC022307
Related Products
Product | Cat No. |
---|---|
Ad-h-ATM | ADV-216937 |
AAV-h-ATM-shRNA | shAAV-216937 |
AAV-m-ATM-shRNA | shAAV-253237 |
Ad-h-ATM-shRNA | shADV-216937 |
Ad-m-ATM-shRNA | shADV-253237 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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