WEE1 homolog
Product Name: Ad-WEE1
Product Category: human Adenovirus Type5 (dE1/E3)
Gene Name: WEE1
Gene Alias: WEE1,WEE1HU
GeneBank Number: BC051831
Description: Phosphorylation of Cdc2 on threonine 14 and tyrosine 15 is required to maintain Cdc2 in an inactive state throughout the S and G2 phases of the cell cycle. The human Wee 1 protein, Wee 1 Hu, encodes a tyrosine-specific protein kinase that phosphorylates Cdc2 on tyrosine 15. Myt 1, a member of the Wee 1 family of protein kinases, has been shown to phosphorylate Cdc2 on both threonine 14 and tyrosine 15 in a cyclin-dependent manner. Both Wee 1 Hu and Myt 1 activity are regulated during the cell cycle, suggesting that both proteins play a role in mitotic control. Dephosphorylation of Cdc2 on threonine 14 and tyrosine 15 in late G2 by Cdc25 then activates the Cdc2/cyclin B complex to allow entry into mitosis.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
| Cat. No. |
Tag |
Promoter |
|
Species |
Price ** |
Availability |
 |
| 1459 |
|
CMV |
|
human |
$445.00 |
In Stock |
|
