Baculoviral IAP repeat-containing 4
Product Name: Ad-BIRC4/XIAP
Product Category: human Adenovirus Type5 (dE1/E3)
Gene Name: BIRC4/XIAP
Gene Alias: API3,ILP1,MIHA,XIAP,BIRC4
GeneBank Number: BC032729
Description: The protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
References: - 17-Allylamino-17-Demethoxygeldanamycin and MEK1/2 Inhibitors Kill GI Tumor Cells via Ca2+-Dependent Suppression of GRP78/BiP and Induction of Ceramide and Reactive Oxygen Species
Mol Cancer Ther. 2010. 9(XX):1378 - Inhibition of Multiple Protective Signaling Pathways and Ad. 5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma
Molecular Therapy. 2010. 18:1130-1142
| Cat. No. |
Tag |
Promoter |
|
Species |
Price ** |
Availability |
 |
| 1429 |
|
CMV |
|
human |
$445.00 |
In Stock |
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