Protein phosphatase 1A (formerly 2C), alpha isoform adenovirus
Product Name: Ad-PP1A
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Gene Name: PP1A
Gene Alias: PPM1A, PP2CA, MGC9201, PP2C-ALPHA
GeneBank Number: BC026691
Description: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1405 |
|
CMV |
|
human |
$690.00 |
|
