Phosphodiesterase 1C, calmodulin-dependent 70kDa adenovirus
Product Name: Ad-PDE1C
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Gene Name: PDE1C
Gene Alias: HCAM3,PDE1C
GeneBank Number: BC022479
Description: The cyclic nucleotide phosphodiesterases (PDEs) have an important role to play in the regulation of cyclic nucleotide levels, as PDE activity hydrolyses camp and cGMP [1-5]. The PDEs are a large superfamily of enzymes consisting of eleven discovered isozyme families (PDE1-11) that differ in respect to substrate specificity, subcellular distribution and regulatory properties [2, 3, 6-9]. Of these eleven families, cGMP-activated PDE (PDE3), cAMP-specific PDE (PDE4), and the more recently discovered PDE7 and PDE8 isozymes mainly hydrolyse cAMP. The PDE5, PDE6 and PDE9 isozymes prefer cGMP as a substrate. Calcium/calmodulin-stimulated PDE (PDE1), cGMP-stimulated PDE (PDE2), PDE10 and PDE11 are dual-substrate PDEs that hydrolyse both cAMP and cGMP.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1388 |
|
CMV |
|
human |
$690.00 |
|
