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BCL2-related protein A1 adenovirus


Product Name: Ad-Bcl2A1

Product Category: Ready-use human Adenovirus Type5 (dE1/E3)

Gene Name: Bcl2A1

Gene Alias: (Bfl-1, anti-apopotosis) GRS,BFL1,HBPA1,BCL2A1,BCL2L5

GeneBank Number: BC016281

Description:

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.

Titer: 1x1010 PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

Catalog No. Tag Promoter Species Price **
1377 CMV human $690.00

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