Endothelin 1 adenovirus
Product Name: Ad-ET-1
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Gene Name: ET-1
Gene Alias: ET1,EDN1
GeneBank Number: BC009720
Description: The endothelins are family of cysteine-rich peptides consisting of 21-amino acid and containing two intramolecular disulfide bridges that exert their vasoactive and mitogenic actions through G protein-coupled receptors. At the present, the existence of three active isoforms of ET (-1, -2, and -3), and two distinct receptors, ETA and ETB, is well documented (17). The active form of ET-1 arises from biologically inactive big-ET-1 through the action of a specific protease that removes 18 amino acids from its carboxyl terminal. This membrane-bound metallopeptidase, characterized by its sensitivity to phosphoramidon, is known as endothelin-converting enzyme-1 (ECE-1) . A growing body of evidence indicate that ET-1 is a major player in numerous disease states including congestive heart failure, pulmonary fibrosis, obesity and diabetes, as well as a key mediator of tissue repair and normal wound healing.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1373 |
|
CMV |
|
human |
$690.00 |
|
