APC
Product Name: Ad-CBR
Product Category: human Adenovirus Type5 (dE1/E3)
Description: Adenomatous polyposis coli gene (APC) is a tumor suppressor gene located on chromosome 5q2. It is inactivated in most colorectal tumors. APC is a cytoplasmic protein that can bind to and promote the degradation of b-catenin. In most colorectal tumors, APC is inactivated. This increases the interaction between b-catenin and Tcf family of transcription factors, leading to increase transcription of genes such as c-Myc.
This adenovirus contains APC mini-me fragment.
Shih IM., et al., Cancer Res. 2000 Mar 15;60(6):1671-6.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
| Cat. No. |
Tag |
Promoter |
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Species |
Price ** |
Availability |
 |
| 1283 |
GFP |
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Human |
$445.00 |
In Stock |
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