NIK adenovirus
Product Name: Ad-CMV-NIK
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Description: NFκB-Inducing Kinase (NIK)
The NFκB transcription factor can be activated by several
cytokines including TNF and IL-1. The TNF receptor activates
NFκB through the Traf2 adapter protein , whereas the IL-1
receptor activates NFκB in a pathway involving Traf6 . Both
Traf2 and Traf6 have been shown to interact with a
serine/threonine kinase designated NFkB inducing kinase (NIK),
which appears to participate in the NFκB signaling cascades
triggered by both TNF and IL-1. NIK associates with, and is
a costimulator for IkB kinase α (IKKα). IKKα , in turn,
phosphorylates IκB, resulting in I κ B degradation and NF κ B
activation. NIK has sequence similarity to several kinases that
participate in MAP kinase cascades.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1180 |
|
CMV |
|
|
$475.00 |
|
