mouse NOX4 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-265956
Availability:
Immediate
Name:
Ad-m-NOX4
This is an Adenovirus expressing Mouse Nox4.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Nox4
- Gene Name
- NADPH oxidase 4
- Gene ID
- 50490
- Gene Synonyms
- AI648021
- ORF Size
- 1737 bp
- RefSeq#
- BC138918
- Gene Description
- Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 4 displays an increased activity. Isoform 5 and isoform 6 display reduced activity.
- UniGene ID
- Mm.31748
Product Citations
This product is referenced in the following publications:
Related Products
Product | Cat No. |
---|---|
AAV-h-NOX4 | AAV-230059 |
AAV-m-NOX4 | AAV-265956 |
Ad-h-NOX4 | ADV-230059 |
AAV-h-NOX4-shRNA | shAAV-230059 |
AAV-m-NOX4-shRNA | shAAV-265956 |
Ad-h-NOX4-shRNA | shADV-230059 |
Ad-m-NOX4-shRNA | shADV-265956 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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